Products

MALEQUIL (120 Capsules)

$46.20

120 Capsules

  • Antioxidant Activity, Detoxification, Male Health*
  • Supports Balance of Male Hormone Metabolism*
  • May Ease Common Symptoms of Excess Testosterone and Estrogen*
  • Promotes Testosterone and Estrogen Metabolism and Detoxification*
  • Provides Antioxidant and Cellular Support*

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Description

MALEQUIL delivers biologically active folate and other key methylation vitamins in combination with a targeted blend of ingredients to encourage hormone balance, help modify xenoestrogen activity, and restore tranquility. Testosterone will convert to estradiol via the aromatase enzyme. (Many factors increase this activity of the aromatase enzyme. Its activity is increased by insulin resistance, low thyroid, abnormal cortisol, leptin, inflammatory cytokines, Roundup, lack of zinc, and vitamin C.) The estrogen produced must be metabolized efficiently and safely. Vitex and black cohosh provide traditional hormone-balancing support; DIM, calcium D-glucarate, and 8-prenylnaringenin (from hops extract) promote estrogen detoxification; and rosemary, resveratrol, grape seed extract, and green tea extract provide antioxidant activity.*

 

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Directions

Take two capsules twice daily, or as directed by your healthcare practitioner.

Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner. Do not use if tamper seal is damaged.

Other Ingredients

Capsule (hypromellose and water), maltodextrin, ascorbyl palmitate, microcrystalline celluose, silica, L-leucine, tricalcium phosphate, and hydroxypropyl cellulose.

Storage

Keep closed in a cool, dry place out of reach of children.

Does Not Contain

Wheat, gluten, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

Supplement Facts

Serving Size: 2 Capsules Servings Per Container: 60

Other products containing Diindolylmethane

Other products containing Green Tea Extract

Other products containing Black Cohosh Extract

Other products containing Chaste Tree Extract

Other products containing Rosemary Extract

Other products containing Grape Seed Extract

Other products containing truebroc® Glucoraphanin

Other products containing 8-prenylnaringenin

  Amount Per Serving %Daily Value
Vitamin B6 (as pyridoxine HCl and pyridoxal 5’-phosphate) 15 mg 882%
Folate as Quatrefolic® (6S)-5-methyltetrahydrofolic acid, glucosamine salt) 200 mcg DFE 50%
Vitamin B12 (as MecobalActive™ methylcobalamin) 200 mcg 8333%
Calcium (as DimaCal® dicalcium malate, calcium D-glucarate, and TRAACS® calcium bisglycinate chelate 60 mg 5%
Magnesium (as Albion® dimagnesium malate) 25 mg 6%
Calcium-D-Glucarate 100 mg **
Diindolylmethane (DIM) 50 mg **
Green Tea Extract (Camellia sinensis)(leaf)(98% polyphenols, 75% catechins, and 45% EGCG) 50 mg **
Black Cohosh Extract (Cimicifuga racemosa)(root and rhizome) (2.5% triterpene glycosides) 50 mg **
Chaste Tree Extract (Vitex agnus-castus)(berry)(0.6% aucubin and 0.5% agnuside) 50 mg **
Turmeric Extract (Curcuma longa)(root)(95% curcuminoids) 25 mg **
Rosemary Extract (Rosmarinus officinalis)(leaf)(5% rosmarinic acid) 25 mg **
trans-Resveratrol (from Polygonum cuspidatum)(root) 20 mg **
Grape Seed Extract (Vitis vinifera)(seeds)(95% proanthocyanidins) 12.5 mg **
truebroc® Glucoraphanin (from broccoli extract)(Brassica oleracea italica)(seed) 4.5 mg **
8-prenylnaringenin (from hops extract)(Humulus lupulus)(cones) 100 mcg **
PATENT INFO:
MecobalActive™ is a trademark of Ferrer Health Tech.

Produced under US patent 6,521,818 licensed from Brassica Protection Products LLC; truebroc is a registered trademark of Brassica Protection Products LLC.

Quatrefolic® is a registered trademark of Gnosis S.p.A. Produced under US patent 7,947,662.

Albion®, DimaCal®, TRAACS® and the Albion Gold Medallion design are registered trademarks of Albion Laboratories, Inc. Malates covered by U.S. Patent 6,706,904.

Calcium D-glucarate is licensed from Applied Food Sciences, Inc. and is protected by US patent 7,662,863.

Femquil

 Amount Per Serving %Daily Value
‡ Percent Daily Values are based on a 2,000 calorie diet.
** Daily Value not established.

Scientific Information/Data

 

 

References

1. Singleton DW, Khan SA. Xenoestrogen exposure and mechanisms of endocrine disruption. Front Biosci. 2003 Jan 1;8:s110-8. Review. [PMID: 12456297]

2. Nadal A, Ropero AB, Laribi O, et al. Nongenomic actions of estrogens and xenoestrogens by binding at a plasma membrane receptor unrelated to estrogen receptor alpha and estrogen receptor beta. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11603-8. [PMID: 11027358]

3. Schellenberg R, Zimmermann C, Drewe J, et al. Dose-dependent efficacy of the Vitex agnus castus extract Ze 440 in patients suffering from premenstrual syndrome. Phytomedicine. 2012 Nov 15;19(14):1325-31. [PMID: 23022391]

4. Zamani M, Neghab N, Torabian S. Therapeutic effect of Vitex agnus castus in patients with premenstrual syndrome. Acta Med Iran. 2012;50(2):101-06. [PMID: 22359078]

5. Roemheld-Hamm B. Chasteberry. Am Fam Physician. 2005 Sep 1;72(5):821-24. [PMID: 16156340]

6. Schellenberg R. Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo controlled study. BMJ. 2001 Jan 20;322(7279):134-37. [PMID: 11159568]

7. Chopin LB. Vitex agnus castus essential oil and menopausal balance: a research update. Complement Ther Nurs Midwifery. 2003 Aug;9(3):157-60. [PMID: 12852933]

8. Geller SE, Studee L. Botanical and dietary supplements for menopausal symptoms: what works, what does not. J Womens Health (Larchmt). 2005 Sep;14(7):634-49. [PMID: 16181020]

9. Nappi RE, Malavasi B, Brundu B, et al. Efficacy of Cimicifuga racemosa on climacteric complaints: a randomized study versus low-dose transdermal estradiol. Gynecol Endocrinol. 2005 Jan;20(1):30-5. [PMID: 15969244]

10. Ruhlen RL, Sun GY, Sauter ER. Black cohosh: insights into its mechanism(s) of action. Integr Med Insights. 2008;3:21-32. [PMID: 21614156]

11. Lieberman S. A review of the effectiveness of Cimicifuga racemosa (black cohosh) for the symptoms of menopause. J. Women’s Health. 1998 June;7(5):525-9. [PMID: 9650153]

12. Mohammad-Alizadeh-Charandabi S, Shahnazi M, Nahaee J, et al. Efficacy of black cohosh (Cimicifuga racemosa L.) in treating early symptoms of menopause: a randomized clinical trial. Chin Med. 2013 Nov 1;8(1):20. [PMID: 24499633]

13. Overk CR, Yao P, Chadwick LR, et al. Comparison of the in vitro estrogenic activities of compounds from hops (Humulus lupulus) and red clover (Trifolium pratense). J Agric Food Chem. 2005 Aug 10;53(16):6246-53. [PMID: 16076101]

14. Bowe J, Li XF, Kinsey-Jones J, et al. The hop phytoestrogen, 8-prenylnaringenin, reverses the ovariectomy-induced rise in skin temperature in an animal model of menopausal hot flushes. J Endocrinol. 2006 Nov;191(2):399-405. [PMID: 17088409]

15. Heyerick A, Vervarcke S, Depypere H, et al. A first prospective, randomized, doubleblind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts. Maturitas. 2006 May 20;54(2):164-75. [PMID: 16321485]

16. Erkkola R, Vervarcke S, Vansteelandt S, et al. A randomized, double-blind, placebo controlled, cross-over pilot study on the use of a standardized hop extract to alleviate menopausal discomforts. Phytomedicine. 2010 May;17(6):389-96. [PMID: 20167461]

17. Monteiro R, Faria A, Azevedo I, et al. Modulation of breast cancer cell survival by aromatase inhibiting hop (Humulus lupulus L.) flavonoids. J Steroid Biochem Mol Biol. 2007 Jun-Jul;105(1-5):124-30. [PMID: 17643984]

18. van Meeuwen JA, Nijmeijer S, Mutarapat T, et al. Aromatase inhibition by synthetic lactones and flavonoids in human placental microsomes and breast fibroblasts—a comparative study. Toxicol Appl Pharmacol. 2008 May 1;228(3):269-76. [PMID: 18201740]

19. Lord RS, Bongiovanni B, Bralley JA. Estrogen metabolism and the diet-cancer connection: rationale for assessing the ratio of urinary hydroxylated estrogen metabolites. Altern Med Rev. 2002 Apr;7(2):112-29. [PMID: 11991791]

20. Bradlow HL. Review. Indole-3-carbinol as a chemoprotective agent in breast and prostate cancer. In Vivo. 2008 Jul-Aug;22(4):441-5. [PMID: 18712169]

21. Riby JE, Xue L, Chatterji U, et al. Activation and potentiation of interferon-gamma signaling by 3,3’-diindolylmethane in MCF-7 breast cancer cells. Mol Pharmacol. 2006 Feb;69(2):430-9. [PMID: 16267208]

22. Cavalieri E, Frenkel K, Liehr JG, et al. Estrogens as endogenous genotoxic agents— DNA adducts and mutations. J Natl Cancer Inst Monogr. 2000;(27):75-93. [PMID: 10963621]

23. Keum YS. Regulation of the Keap1/Nrf2 system by chemopreventive sulforaphane: implications of posttranslational modifications. Ann N Y Acad Sci. 2011 Jul;1229:184-89. [PMID: 21793854]

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