When discussing any organ system in the body it’s important to understand that organs do not work in isolation; everything works as a whole system. For example, the thyroid function may be affected by environmental influence such as diet, nutrition, exercise and trauma. Immune and inflammatory imbalance, oxidative stress and energy production, gastrointestinal status, detoxification, musculoskeletal structures, other hormones and neurotransmitters, mind, spirit, emotions, and community may also affect it, as may genetic predisposition. All these factors should be evaluated to return the thyroid from a dysfunction state to a normal functioning organ.