Excess estrogen is associated with central body weight gain, breast tenderness, heavy menses and panic attacks. Control insulin with ALAmed CR and/or Alamax Protect and/or Berberine and/or Glysen or Glysen Synergy, and/or Glucose Modulate. Glucose Modulate has chromium along with vitamins, herbs and minerals important for insulin/glucose levels. Chromate GTF 600 has chromium polynicotinate if you want to take only chromium for blood glucose/insulin support. Block aromatase and improve detoxification of excess estrogen with Hepato DPO and/or Xeno Detox. Other supplements that help are Mag-nificent, Optimag, DIM-3, DIMension-3 or HormonE.