Scientific Information/Data
Good nutrition is a basis for wellness, and good nutrition usually translates into a stronger immune system and better health. An important aspect of good nutrition is micronutrition (vitamins and minerals).[1-4] Micronutrients participate in converting food into energy; building and repairing tissues and DNA; manufacturing neurotransmitters, hormones, and other modulators in the body; breaking down and detoxifying xenobiotics and medications; and maintaining growth, reproduction, and health.*
According to research by the USDA and other organizations, Americans are lacking key micronutrients.[5-8] Mass food production, storage techniques, poor food choices, and nutrient-depleting preparation methods may contribute to inadequacies. Nutrient intake data from a representative sample of the US population aged 2 years and older indicate that vitamins A, D, E, C, and folate, calcium, and magnesium are underconsumed relative to the estimated average requirements (EARs). What’s more, some functional medicine practitioners believe that therecommended intakes (e.g., %DV, DRIs, EARs, RDAs) may not meet the requirements of all individuals, especially the chronically ill. The bottom line is that children and adults are not consuming enough nutrient-rich foods to meet all their most basic vitamin and mineral needs.*[6]
There are numerous reasons to select ActivNutrients without Copper and Iron Multivitamin Powder:
Complete, Minus Copper and Iron This formula features a wide variety of important nutrients in significant amounts, including calcium and magnesium, vitamins C and E, bioactive folate, B complex, beta-carotene, and trace elements. ActivNutrients without Copper and Iron Multivitamin Powder provides the option to add copper and/or iron only when needed, such as when indicated by laboratory testing.*
Bioavailability The micronutrients are provided in forms that can be optimally absorbed and utilized. ActivNutrients without Copper and Iron Multivitamin Powder contains a full complement of Albion® patented mineral chelates and complexes. Albion is a recognized world leader in mineral amino acid chelate nutrition and manufactures highly bioavailable minerals that are validated by third-party research and clinical studies.* Not only does this formula contain natural vitamin E, which has been proven to be up to 100% more bioavailable than synthetic dl-alphatocopherol, but it also provides mixed tocopherols to more closely approximate how vitamin E occurs naturally in whole foods.[9,10] Folate is provided as 5-methyltetrahydrofolate (5-MTHF), the most bioactive form of folate.[11] This formula features 5-MTHF as Quatrefolic®, which is proven to have greater stability, solubility, and bioavailability when compared to the calcium salt form of 5-MTHF.[12] Vitamin B12 is provided as MecobalActive™. This patented form of methylcobalamin has very high purity; no harmful solvents are used in its production.[13] Vitamins B2 and B6 are also provided in activated forms.*
Energy Production ActivNutrients without Copper and Iron Multivitamin Powder provides generous levels of B vitamins, which serve as prime coenzymes in glycolysis and oxidative phosphorylation (steps in energy production) and as cofactors in amino acid and lipid metabolism. The balanced presence of B vitamins is essential to their cooperative functioning and excellent for growing children as well as adults with stressful lifestyles.*
Antioxidant Protection Vitamins E and C; selenium; zinc; lemon bioflavonoids; mixed carotenoids, including alpha- and beta-carotene, gamma-carotene, and lycopene; and trace elements provide broadspectrum antioxidant activity. The combination of these nutrients provides broad spectrum intra- and extracellular antioxidant support.*
Detoxification Support Xenobiotics, including environmental pollutants and medications, must undergo biotransformation into molecules that can be easily excreted from the body. Artificial colors and flavors, additives, preservatives, and pesticides all increase demands on the body’s detoxification processes, which require vitamins and minerals. There are significant levels of bioavailable riboflavin, niacin, folate, and B12 present in these formulas to support phase I detoxification. Beta carotene, vitamin C, tocopherols, selenium, and zinc are present to protect tissues from reactive intermediates formed between phase I and phase II detoxification.*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
References
1. Ames BN. A role for supplements in optimizing health: the metabolic tune-up. Arch Biochem Biophys. 2004 Mar 1;423(1):227-34. [PMID: 14989256]
2. Ward E. Addressing nutritional gaps with multivitamin and mineral supplements. Nutr J. 2014 Jul 15;13:72. [PMID: 25027766]
3. Block G, Jensen CD, Norkus EP, et al. Usage patterns, health, and nutritional status of long-term multiple dietary supplement users: a cross-sectional study. Nutr J. 2007 Oct 24;6:30. [PMID: 17958896]
4. Lam LF, Lawlis TR. Feeding the brain – The effects of micronutrient interventions on cognitive performance among school-aged children: A systematic review of randomized controlled trials. Clin Nutr. 2016 Jun 23. [PMID: 27395329]
5. Moshfegh AJ, Goldman JD, Ahuja JK, et al. U.S. Department of Agriculture, Agricultural Research Service. What we eat in America, Nhanes 2005-2006. Usual nutrient intakes from food and water compared to 1997 dietary reference intakes for vitamin D, calcium, phosphorus, and magnesium. http://www.ars.usda.gov/SP2UserFiles/Place/12355000/pdf/0506/usual_nutrient_intake_ vitD_ca_phos_mg_2005-06.pdf Published July 2009. Accessed September 22, 2016.
6. Fulgoni VL 3rd, Keast DR, Bailey RL, et al. Foods, fortificants, and supplements: Where do Americans get their nutrients? J Nutr. 2011 Oct;141(10):1847-54. [PMID: 21865568]
7. Milk Processor Education Program. What America’s Missing: A 2011 Report on the Nation’s Nutrient Gap. https://milklife.com/articles/nutrition/what-americasmissing. Accessed September 23, 2016.
8. Alexy U, Libuda L, Mersmann S, et al. Convenience foods in children’s diet and association with dietary quality and body weight status. Eur J Clin Nutr. 2011 Feb;65(2):160-66. [PMID: 21139631]
9. Kiyose C, Muramatsu R, Kameyama Y, et al. Biodiscrimination of alphatocopherol stereoisomers in humans after oral administration. Am J Clin Nutr. 1997 Mar;65(3):785-89. [PMID: 9062530]
10. Burton GW, Traber MG, Acuff RV, et al. Human plasma and tissue alphatocopherol concentrations in response to supplementation with deuterated natural and synthetic vitamin E. Am J Clin Nutr. 1998 Apr;67(4):669-84. [PMID: 9537614]
11. Venn BJ, Green TJ, Moser R, et al. Comparison of the effect of low-dose supplementation with L-5-methyltetrahydrofolate or folic acid on plasma homocysteine: a randomized placebo-controlled study. Am J Clin Nutr. 2003 Mar;77(3):658-62. [PMID: 12600857]
12. Crossover Comparative Bioavailability Study of 5-Methyltetrahydrofolate Glucosamine Salt (GN10G) Compared to the Reference Metafolin® in Healthy Volunteers. IPAS-5MTHFA-583-09 final report. Desio, Italy: Gnosis S.p.A.; March15, 2010: 1-33. [available from the manufacturer Gnosis S.p.A. upon request]
13. Sallares J, Petschen I, Camps X, inventors; Ferrar Internacional, S.A., applicant. Process for the production of methylcobalamin. International publication number [English] WO 2006100059 A1. September 28, 2006.
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