Revitalizing Aging Cells through AMPK Activation
Found in every cell,1,2 AMPK promotes longevity factors that have been shown to extend life span in numerous organisms.3,4 Increasing AMPK signaling “turns off” many damaging effects of aging, thus enabling cells to return to their youthful vitality.5*
Life Extension® scientists have compiled years of research to create AMPK Activator, a specialized dual-extract formulation that supports AMPK activation for health optimization. This natural formula supports AMPK enzymatic activities required to safely support a more youthful cellular environment.*
Importance of AMPK Activation
Greater AMPK activation has been shown to help target damaging factors of aging.5 Studies show increased AMPK activity supports reduced fat storage,6-8 new mitochondria production,9 and the promotion of healthy blood glucose and lipids already within normal range.4,10*
Gynostemma Pentaphyllum Promotes Longevity and Fights Fat
An extract of the plant Gynostemma pentaphyllum was traditionally used in Asian medicine to promote longevity and scientists now know why — G. pentaphyllum promotes AMPK activation.10,11 In one of many studies showing a wide variety of benefits, researchers documented a 1-inch reduction in abdominal circumference on average in overweight individuals who took 450 mg daily of G. pentaphyllum extract for 12 weeks.8*
Rose Hips Provides Metabolic Benefits
Trans-tiliroside, extracted from plants such as rose hips, also boosts AMPK activation, but triggers different downstream metabolic benefits than G. pentaphyllum.12-14 Among its many benefits, a low human equivalent dose of 56 mg daily trans-tiliroside has been shown by researchers in preclinical studies to promote healthy blood glucose levels and body weight already within normal range.15*
Anti-Aging Discovery That Cannot be Overlooked
Scientists uncovered the cell-energizing effect of AMPK in the 1970s. Since then, an exponential volume of data (over 8,500 published studies) has documented the critical role that activated AMPK plays in maintaining life-sustaining cellular functions.*
If you’d like to meaningfully extend your healthy life span, activating your cellular AMPK is critical. This is important because in response to aging, excess calorie consumption, and/or low levels of physical activity, AMPK activity markedly declines.*
You can fight AMPK decline with regular exercise and avoiding excessive calories … but it may not be enough. Our AMPK Activator formula is a targeted way to reverse cellular depletion of the critical AMPK enzyme.*
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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- J Nutr Biochem. 2012 Jul;23(7):768-76.
- Bioorg Med Chem Lett. 2007 Jun 1;17(11):3059-64.